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The major histocompatibility complex (MHC) of the water vole
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Information is provided about the current state of knowledge on the MHC selection
in the water Vole.
- The slide-show (39 slides) reviews the MHC selection mechanisms at various time
scales (contemporary, historical) as they are known in voles. Some detection methods
are also overviewed.
- four articles addressing focus aspects of the MHC selection are made available :
. Bryja et al., 2006: Duplication, balancing selection and trans-species evolution
explain the high levels of polymorphism of the DQA MHC class II gene in voles
(Arvicolinae).
. Bryja et al., 2007: Density-related changes in selection pattern for major
histocompatibility complex genes in fluctuating populations of voles.
. Deter et al., 2008: Association between the DQA MHC class II gene and
Puumala virus infection in Myodes glareolus, the bank vole.
. Tollenaere et al., 2008: Multiple parasites mediate balancing selection at two
MHC class II genes in the fossorial water vole: insights from multivariate analyses
and population genetics.
- Generic Wiki article on MHC are also provided for convenience.